Louis J Nkrumah, MD, PhD

PGY-7

Department of Neurosurgery, Emory University School of Medicine

Education

  • BS, MS, Yale University, 2000
  • MD, PhD, Albert Einstein College of Medicine, 2008

Biography

Hometown: Kumasi, Ghana

Areas of Interests

  • Spine 
  • Neuro-oncology

Future Plans

  • Academics

Awards/Grants

  • 2008 Albert Einstein College of Medicine Dean’s Recognition Award

Memberships

Hobbies

  • Soccer
  • Martial arts

Publications

  • Lalaker A, Nkrumah L, Lee WK, Ramanathan M, Lane AP. (2009) Chitin stimulates expression of acidic mammalian chitinase and eotaxin-3 by human sinonasal epithelial cells in vitro. Am J Rhinol Allergy. 23(1):8-14.
  • Muhle RA, Adjalley S, Falkard B, Nkrumah LJ, Muhle ME, Fidock DA. (2009) A var gene promoter implicated in severe malaria nucleates silencing and is regulated by 3’ untranslated region and intronic cis-elements. Int J Parasitol. 39(13): 1425-39
  • Nkrumah LJ, Riegelhaupt PM, Moura P, Johnson DJ, Patel J, Hayton K, Ferdig MT, Wellems TE, Akabas MH, Fidock DA. (2009) Probing the multifactorial basis of Plasmodium falciparum quinine resistance: evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE. Mol Biochem Parasitol. 165(2):122-31.
  • Yu M, Kumar TR, Nkrumah LJ, Coppi A, Retzlaff S, Li CD, Kelly BJ, Moura PA, Lakshmanan V, Freundlich JS, Valderramos JC, Vilcheze C, Siedner M, Tsai JH, Falkard B, Sidhu AB, Purcell LA, Gratraud P, Kremer L, Waters AP, Schiehser G, Jacobus DP, Janse CJ, Ager A, Jacobs WR Jr, Sacchettini JC, Heussler V, Sinnis P, Fidock DA. (2008) The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites. Cell Host Microbe. 4(6):567-78.
  • Freundlich JS, Wang F, Tsai HC, Kuo M, Shieh HM, Anderson JW, Nkrumah LJ, Valderramos JC, Yu M, Kumar TR, Valderramos SG, Jacobs WR Jr, Schiehser GA, Jacobus DP, Fidock DA, Sacchettini JC. (2007) X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy. J Biol Chem. 31;282(35):25436-44.
  • Sidhu AB, Sun Q, Nkrumah LJ, Dunne MW, Sacchettini JC, and Fidock DA. (2007) In vitro efficacy, resistance selection and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin. J. Biol. Chem. 282 (4): 2494-2504
  • Nkrumah LJ, Muhle RA, Moura PM, Ghosh P, Hatfull GF, Jacobs WR Jr., and Fidock DA. (2006) Efficient site-specific integration system in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase. Nature Methods (3): 615 – 621
  • Furuya T, Mu J, Hayton K, Liu A, Duan J, Nkrumah L, Joy DA, Fidock DA, Fujioka H, Vaidya AB, Wellems TE, Su XZ. (2005) Disruption of a Plasmodium falciparum gene linked to male sexual development causes early arrest in gametocytogenesis. Proc Natl Acad Sci USA 102(406):16813-8.