Our current laboratory effort has four primary research projects:
- 1) defining protein associations and signaling networks that underlie specific tumor cell characteristics including glioma cell migration, cytoskeletal rearrangements, extracellular matrix interactions, metabolism, and glioma stem cells;
- 2) evaluating ways to more specifically target glioma cells with fluorescent probes that may aid in surgical resections;
- 3) comparing genomic and proteomic signatures between Western and African society meningiomas to better understand the differences in these patient populations; and
- 4) utilizing local institutional and large national clinical databases to better characterize various brain tumor patients and responses to treatments.