David Gimbel, MD, MHS

    Assistant Professor

    Emory University Department of Neurosurgery

    Education

    • BS, Yale University, 2003
    • MD, Yale University, 2010
    • Residency, Yale University, 2017
    • Complex Spine Fellowship, University of Cincinnati, 2018

    Biography

    Honors

    • Yale University Department of Neurosurgery Resident Research Award, 2015
    • The William U. Gardner Prize – awarded to the graduating student with the most outstanding thesis in the Yale Medical School graduating class, 2010
    • Yale Medical School Endowed Research Fellowship Recipient, 2007-08
    • Farr Scholar - Excellence in Research as a Yale Medical Student, 2007
    • NIH T32 Research Training Grant Recipient, 2006-07
    • Yale University School of Medicine Summer Research Award, 2004-05
    • President, Morse College (Yale University), 2002-03
    • National Merit Scholarship Finalist, National AP Scholar, 1999

     

    Publications

    Peer Reviewed Publications

    • Gimbel DA, Nygaard HB, Coffey EE, Gunther EC, Lauren J, Gimbel ZA, Strittmatter SM. Memory impairment in transgenic Alzheimer mice requires cellular prion protein. J Neurosci. 2010 May 5;30(18):6367-74
    • Lauren J, Gimbel DA, Nygaard HB, Gilbert JW, Strittmatter SM. Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. Nature. 2009 Feb 26;457(7233):1128-32
    • Park JH, Widi GA, Gimbel DA, Harel NY, Lee DH, Strittmatter SM. Subcutaneous Nogo receptor removes brain amyloid-beta and improves spatial memory in Alzheimer’s transgenic mice. J Neurosci. 2006 Dec 20;26(51):13279-86
    • Park JH, Gimbel DA, Grandpre T, Lee JK, Li W, Lee DH, Strittmatter SM. Alzheimer precursor protein interaction with the Nogo-66 receptor reduces amyloid-beta plaque deposition. J Neurosci. 2006 Feb 1;26(5):1386-95
    • Marklund N, Morales D, Clausen F, Hanell A, Kiwanuka O, Pitkanen A, Gimbel DA, Philipson O, Lannfelt L, Strittmatter SM, McIntosh TK. Functional Outcome Is Impaired Following Traumatic Brain Injury in Aging NogoA/B-Deficient Mice. Neuroscience. 2009 Oct 6;163(2):540-51
    • Hanell A, Clausen F, Bjork M, Jansson K, Philipson O, Nilsson LN, Hillered L, Weinreb PH, Lee D, McIntosh TK, Gimbel DA, Strittmatter SM, Marklund N. Genetic deletion and pharmacological inhibition of Nogo-66 receptor impairs cognitive outcome after traumatic brain injury in mice. J Neurotrauma. 2010 Jul;27(7): 1297-309.
    • Bulsara KR, Hebert R, Gimbel D, Abbed, K. Type I spinal arteriovenous fistulae exception:  a case for reclassification. Neurochirurgie. 2013 Apr;59(2):69-74.

    Intellectual Property

    • Cellular Prion Protein as a Receptor for Alzheimer’s Disease Therapeutics Patented through the Yale University Office of Cooperative Research

    Poster Presentations

    • Gimbel DA, O’Brien R, Schmerler J, Fink, KL, Strittmatter SM, and Cafferty WB. In vivo pathways of structural reorganization responsible for recovery in spinal cord injury (SCI).  Society for Neuroscience, October 2017
    • Gimbel DA, Coffey E, Nygaard H, Strittmatter SM. Alzheimer’s transgenic phenotypes in mice lacking cellular Prion Protein expression. Society for Neuroscience, October 2009